Tuesday, September 16, 2014

Surgery Options for Epilepsy

On Friday, I went to the epilepsy support group meeting of the Epilepsy Support Network of Orange County.  We had an excellent speaker,Dr. Mary Zupanc, pediatric epileptologist of Children’s Hospital of Orange County (CHOC) and University of California—Irvine.  She talked about new surgery options for epilepsy. 


She started her presentation by stating some stark facts.  You have a 60% chance of being seizure free with your first medication.  After that, any other medication you try gives you only a 10% chance of seizure freedom.  Also, she said that success rates are further decreased in today’s society because of family situations.  In 85% of all families with “special-needs” children, the parents are divorced.  As a result, it is often difficult to get them to work together for the good of their child.  If that hurdle can be overcome, decisions will not necessarily be easier, but more team based, so no matter how difficult, it will be done together with no second guessing.

In the past, the go-to treatment has always been medication first.  However, this should not be the way we think today.  As Dr. Zupanc said, you have to diagnose the condition first and then choose the appropriate treatment.  In many cases, surgery is a first-line treatment.  Children especially, whose brains are elastic and adaptable, should take advantage of surgery if they have really debilitating seizures.  After all, the more seizures they have, the more it will slow down their development.

There are the traditional surgeries of cutting out certain parts of the brain where the seizure activity takes place, in any of the four lobes:  temporal, frontal, parietal, occipital.  Then, there is the hemispherectomy in which an entire hemisphere is either taken out or neutralized.  This is done mainly in children.  I don’t think the average adult could imagine him or herself functioning with only one half of his or her brain.

In the pipeline they are working on (1) Deep Brain Stimulation which uses electrodes directly placed on the brain, (2) Responsive Neurostimulation which focuses on targeted areas of the brain before a seizure starts, (3) Gamma Knife Surgery which uses radiation, and (4) Visualase laser surgery. 

I really appreciate those people who participate in these studies.  I admire their courage in trying these treatments in the experimental trial stages. I know some will benefit, but many will not.  Thank you for your volunteering—it will make us all better in the end. 


Deep Brain Stimulation (DBS)

Responsive Neurostimulation (RNS)

Gamma Knife Surgery

Visualase Laser Surgery


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